Separation
Answers to your questions on the topic Separation can be found here.
Proliferating cells differ in size. Does this phenomenon have any effect on the enrichment of tumour cells with OncoQuick®?
No.
The separation principle of OncoQuick® takes advantage of differences in density, but not size. Often circulating tumour cells are non-proliferating cells and as such unaffacted by conventional therapy (chemotherapy, radiotherapy). Such ‘doming cells’ have identical densities.
