Welche ThinCert™ Zellkultur-Einsätze eignen sich für Migrations- und Invasionsstudien?
Zur Durchführung von Migrations- und Invasionsstudien müssen die Membranporen klein genug gewählt werden, um die untersuchten Zellen am passiven Durchtritt zu hindern, jedoch groß genug, dass den Zellen eine Membranpassage durch aktive Migration ermöglicht wird. ThinCertTM Zellkultur-Einsätze mit 3,0- und 8,0 µm-Poren erfüllen diese Voraussetzung.
Download PDF: Forum No. 8 - ThinCertTM
Interessante Literatur:
Bartling B, Hofmann HS, Weigle B, Silber RE, Simm A.
Down-regulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma. Carcinogenesis. 2005 Feb;26(2):293-301. Epub 2004 Nov 11.
Dittmer A, Vetter M, Schunke D, Span PN, Sweep F, Thomssen C, Dittmer J.
Parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells.
J Biol Chem. 2006 May 26;281(21):14563-72. Epub 2006 Mar 21.
Hiscox S, Jiang WG, Obermeier K, Taylor K, Morgan L, Burmi R, Barrow D, Nicholson RI.
Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation. Int J Cancer. 2006 Jan 15;118(2):290-301.
Luo XG, Ding Y, Zhou QF, Ye L, Wang SZ, Xi T.
SET and MYND domain-containing protein 3 decreases sensitivity to dexamethasone and stimulates cell adhesion and migration in NIH3T3 cells.
J Biosci Bioeng. 2007 May;103(5):444-50.
Kitzing TM, Sahadevan AS, Brandt DT, Knieling H, Hannemann S, Fackler OT, Großhans J, Grosse R.
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion.
Genes Dev. 2007 Jun 15;21(12):1478-1483.
Saidi H, Magri G, Carbonneil C, Nasreddine N, Requena M, Belec L.
IFN-gamma-activated monocytes weakly produce HIV-1 but induce the recruitment of HIV-sensitive T cells and enhance the viral production by these recruited T cells.
J Leukoc Biol. 2007 Mar;81(3):642-53. Epub 2006 Sep 13.
Thevenard J, Floquet N, Ramont L, Prost E, Nuzillard JM, Dauchez M, Yezid H, Alix AJ, Maquart FX, Monboisse JC, Brassart-Pasco S.
Structural and antitumor properties of the YSNSG cyclopeptide derived from tumstatin.
Chem Biol. 2006 Dec;13(12):1307-15